{"id":193410,"date":"2026-02-26T06:51:57","date_gmt":"2026-02-26T10:51:57","guid":{"rendered":"https:\/\/infoelnuevonorte.com\/?p=193410"},"modified":"2026-02-26T09:03:40","modified_gmt":"2026-02-26T13:03:40","slug":"un-ensayo-prueba-con-exito-una-unica-pastilla-diaria-que-combina-dos-farmacos-para-el-vih","status":"publish","type":"post","link":"https:\/\/infoelnuevonorte.com\/?p=193410","title":{"rendered":"Un ensayo prueba con \u00e9xito una \u00fanica pastilla diaria que combina dos f\u00e1rmacos para el VIH"},"content":{"rendered":"<!--[if lt IE 9]><script>document.createElement('audio');<\/script><![endif]-->\n<audio class=\"wp-audio-shortcode\" id=\"audio-193410-1\" preload=\"none\" style=\"width: 100%;\" controls=\"controls\"><source type=\"audio\/mpeg\" src=\"https:\/\/infoelnuevonorte.com\/wp-content\/uploads\/2026\/02\/ttsmaker-vip-file-2026-2-26-6-51-19.mp3?_=1\" \/><a href=\"https:\/\/infoelnuevonorte.com\/wp-content\/uploads\/2026\/02\/ttsmaker-vip-file-2026-2-26-6-51-19.mp3\">https:\/\/infoelnuevonorte.com\/wp-content\/uploads\/2026\/02\/ttsmaker-vip-file-2026-2-26-6-51-19.mp3<\/a><\/audio>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">Una sola pastilla diaria, que combina dos medicamentos actuales, se perfila como \"una prometedora alternativa\" a los complejos reg\u00edmenes de tratamiento del VIH con m\u00faltiples comprimidos.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">Esta es la principal conclusi\u00f3n de un ensayo cl\u00ednico en fase III realizado con 557 personas; los detalles se publican en la revista <em>The Lancet<\/em>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">El estudio, llamado ARTISTRY-1, se llev\u00f3 a cabo en 90 hospitales y cl\u00ednicas de Australia, Argentina, Canad\u00e1, Corea del Sur, Espa\u00f1a, Estados Unidos, Francia, Alemania, Italia, Jap\u00f3n, Puerto Rico, la Rep\u00fablica Dominicana, Sud\u00e1frica, Taiw\u00e1n y el Reino Unido.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">La pastilla combina los f\u00e1rmacos bictegravir y lenacapavir y el ensayo demostr\u00f3 que el nuevo tratamiento en un solo comprimido era muy eficaz para mantener la supresi\u00f3n del VIH.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">Casi el 96 % de los 371 participantes que cambiaron a este r\u00e9gimen simplificado mantuvieron la supresi\u00f3n viral sin que se notificaran nuevos casos de resistencia a los medicamentos.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">En comparaci\u00f3n, los 186 voluntarios que continuaron con los tratamientos existentes de m\u00faltiples comprimidos mostraron resultados similares, manteniendo tambi\u00e9n la supresi\u00f3n viral en una proporci\u00f3n de entre el 94 % y el 96 %.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">Por lo tanto, la nueva pastilla podr\u00eda sustituir eficazmente los reg\u00edmenes de tratamiento m\u00e1s complicados, concluyen los autores.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">La media de edad de los participantes era de 60 a\u00f1os (la edad oscilaba entre los 22 y los 84 a\u00f1os) y tomaban un promedio de tres comprimidos antirretrovirales al d\u00eda (con un rango que iba desde 2 a 11 pastillas). Aproximadamente el 40 % de los ellos inger\u00eda antirretrovirales m\u00e1s de una vez al d\u00eda.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">Muchos participantes tambi\u00e9n informaron de otras afecciones de salud, como enfermedades cardiovasculares o renales, y la mayor\u00eda presentaba resistencia a tratamientos previos contra el VIH.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">En el estudio no se identificaron problemas de seguridad significativos o novedosos, y la mayor\u00eda de las personas experimentaron menos efectos secundarios relacionados con los l\u00edpidos, como el aumento de los niveles de colesterol, lo que sugiere un beneficio potencial adicional para aquellas con riesgo de padecer enfermedades card\u00edacas.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">Los participantes informaron de que la nueva opci\u00f3n de tratamiento era m\u00e1s f\u00e1cil y c\u00f3moda de tomar, lo que puede ayudar a mantener una adherencia constante a la medicaci\u00f3n diaria.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">Los autores afirman que esto es especialmente importante para los adultos mayores que viven con el VIH, las personas con antecedentes de resistencia a los tratamientos contra este virus o aquellas que toman medicamentos adicionales para ayudar a controlar afecciones de salud relacionadas con la edad junto con la medicaci\u00f3n contra el VIH.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">En la actualidad, se est\u00e1n llevando a cabo ensayos cl\u00ednicos adicionales para confirmar la seguridad y la eficacia a largo plazo de este comprimido combinado.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">Asimismo, este estudio se presenta en la Conferencia sobre Retrovirus e Infecciones Oportunistas en Denver, Colorado (Estados 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El estudio, llamado ARTISTRY-1, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":193476,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19,13],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Un ensayo prueba con \u00e9xito una \u00fanica pastilla diaria que combina dos f\u00e1rmacos para el VIH | El Nuevo Norte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/infoelnuevonorte.com\/?p=193410\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Un ensayo prueba con \u00e9xito una \u00fanica pastilla diaria que combina dos f\u00e1rmacos para el VIH | El Nuevo Norte\" \/>\n<meta property=\"og:description\" content=\"Una sola pastilla diaria, que combina dos medicamentos actuales, se perfila como &quot;una prometedora alternativa&quot; a los complejos reg\u00edmenes de tratamiento del VIH con m\u00faltiples comprimidos. 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